Marinosolv® enables a strongly increased solubilization and thereby enhanced bioavailability of hydrophobic small molecules and peptides. Consequently, more efficient treatments of a multitude of diseases can be envisaged. Marinosolv® technology facilitates targeted drug delivery with a low systemic off-target activity. Existing drugs and off-patent active ingredients can be improved and re-patented as part of new formulations using Marinosolv®.
Saponins (e.g. Escin, Glycyrrhizin) and Dexpanthenol form micelles in a buffered aqueous solvent. The micelles are self-forming in aqueous solutions and have a hydrophobic core and a hydrophilic outside. The different constituents of the Marinosolv® matrix are individually composed for an optimized formulation of each drug substance.